Mourinho is facing a major issue with positioning Alexis Sanchez, Marcus Rashford, Anthony Martial and Jesse Lingard.
Pogba, 24, missed United's 2-0 win over Huddersfield in the FA Cup fifth round on 17 February due to illness.
England striker Kane, 24, is the top scorer in the Premier League this season with 23 goals in 26 games.
Two fifth round matches have not taken place yet: Rochdale vs Tottenham and Wigan vs Manchester City play on Sunday and Monday respectively.
Lukaku struck very early and finished off wonderful counter-attack to punish the bright but toothless Terriers.
Wanyama, troubled by a serious knee problem this season, is the type of midfielder Steven Gerrard believes the Reds need.
Former Blues midfielder Frank Lampard suggests Christensen is as good as Liverpool's January signing.
Pogba, 24, has failed to complete the full 90 minutes in his last three appearances for United amid a poor run of form.
The likes of Mohamed Salah, Roberto Firmino and Sadio Mane form a potent front three which can put any team under pressure.
Tottenham have not experienced success in the oldest cup competition in the world in nearly three decades.
Bellerin denied there was a breakdown in relationship between Sanchez and the Arsenal dressing room.
Michael Carrick is expected to retire at the end of the season and join Mourinho's coaching team at Manchester United.
Marcos Alonso will be ready to return to action when Barcelona visit Chelsea on Tuesday night, but Tiemoue Bakayoko is likely to miss the Champions League clash.
Harry Kane twisted his ankle and "received some knocks" during Tottenham's 2-2 comeback draw with Juventus in the Champions League on Tuesday, according to Mauricio Pochettino.
Lionel Messi leads Barcelona's 18-man squad for the trip to Eibar as Ernesto Valverde says that his side are still not thinking about their Champìons League tie with Chelsea.
Michael Carrick believes Scott McTominay will eventually replace him in the Manchester United midfield.
Liverpool and Arsenal are out of the FA Cup but the other four from the Premier League's top six are still in with a chance to win.
Eric Bailly is available for Manchester United's FA Cup clash with Huddersfield Town but Marcus Rashford and Ander Herrera remain sidelined.
Ernesto Valverde has been coy about the possibility of losing Andres Iniesta following reports claiming the Barcelona captain could move to China in the summer.
Mooy suffered a knee injury during Huddersfield's much-needed win over Bournemouth on Sunday (11 February) and could miss his side's next three matches.
The Belgium international is close to signing a new contract at Stamford Bridge after Real Madrid gave up their interest.
Real Madrid star Toni Kroos is set to miss the trip to Betis after suffering a knee injury during Los Blancos' 3-1 victory over Paris Saint-Germain.
Sandro Ramirez has ruled out a return to Everton in the summer after claiming that he wants to remain at Sevilla for the long-term.
Manchester United boss Jose Mourinho addresses the media ahead of his side's FA Cup clash against Huddersfield Town.
Manchester City have lost only two games in all competitions this season. They have one foot in the quarter-final of the Champions League after a 4-0 win over Basel.
Michy Batshuayi is not thinking about his future, with the striker on loan from Chelsea enjoying a terrific start to life at Borussia Dortmund.
Brazil's first-choice goalkeeper Alisson was on Liverpool's radar but Roma's £70m valuation and Karius' encouraging performances have led the Reds to look elsewhere.
Barcelona legend Andres Iniesta is considering a tempting offer from to move to the Chinese Super League side Tianjin Quanjian at the end of the season.
Salah made it 2-0 showing incredible skill to finish from close range and notch his 30th goal of an incredible debut season on Merseyside.
Charly Musonda turned in a sublime performance to help Celtic beat Zenit St Petersburg, much to the frustration of Chelsea fans who did not want him to leave on loan.