Manchester United will reportedly step up their scouting of Alex Grimaldo after the left-back impressed Jose Mourinho.
Arsenal majority owner Stan Kroenke has no plans to sell the club having rejected a £1bn offer from Alisher Usmanov earlier this year.
Liverpool will be without the services of forward Sadio Mane, midfielder Adam Lallana, full-back Nathaniel Clyne and backup goalkeeper Adam Bogdan.
Tottenham have been in brilliant form this season and sit level on points with United following their 4-1 thrashing of Liverpool last gameweek.
Harry Kane has been in fine form for Tottenham, scoring 13 goals in 12 appearances in all competitions. His absence will be a massive blow for Spurs against Manchester United.
Round Five of the Carabao Cup draw will be held at Twitter's UK hub in central London at 4pm BST on 26 October, Thursday.
Chelsea star N'Golo Kante is edging closer to making a return to action from the hamstring injury he sustained during the recent international break.
Stan Kroenke remains hopeful that Arsenal can re-sign contract rebels Mesut Ozil and Alexis Sanchez to new deals before the end of the season.
Bournemouth manager Eddie Howe says Callum Wilson could make his Premier League return against Chelsea on Saturday.
The Merseysiders were interested in signing Costa in the summer but the fiery Spaniard eventually returned to Atletico Madrid.
Wales international forward Ben Woodburn wants to earn more senior opportunities after pledging his future to Liverpool for many years to come.
Jurgen Klopp has been urged to overhaul his back-line with the signing of four new defenders in the January transfer window.
Claude Puel has agreed a three-year deal to become Leicester's new manager and will take charge of the Foxes against Everton on Sunday.
Everton host Chelsea in the Carabao Cup fourth round in what is David Unsworth's first match in charge following Ronald Koeman's departure.
Huddersfield will be without Philip Billing for up to 12 weeks after the Danish Under-21 international underwent surgery on an ankle injury suffered at Swansea.
Andre Ayew nets a second-half brace and Angelo Ogbonna heads home the winner as West Ham recover from two goals down to beat Tottenham 3-2 in the Carabao Cup.
Chelsea and Everton battling to reach the last eight of the Carabao Cup amid differing managerial situations.
Barcelona full-back Nelson Semedo says he believes he will one day end up back at boyhood club Benfica later in his career.
Cameron Borthwick-Jackson's desperate loan spell at Leeds United took another turn for the worse after he suffered an ankle injury in his first appearance for a over a month.
Coutinho made no secret of his desire to leave Merseyside for Catalonia in the summer and Heskey thinks his "head may be turned" again in January.
Mesut Ozil will reportedly only leave Arsenal for three clubs – Manchester United, Real Madrid and Barcelona. The German is not interested in moving to Italy or Turkey.
Mauricio Pochettino claims that Daniel Levy does not impose age restrictions on incoming Tottenham transfers, with 32-year-old Fernando Llorente adapting well.
Spanish international Jordi Alba has returned to the Barcelona training sessions ahead of the upcoming trip to Athletic Club Bilbao.
Spurs have not won a trophy in a decade but Pochettino said winning the FA Cup would not be life changing.
Alexis Sanchez's contract at Arsenal will run down after the end of this season. The Chilean was keen on joining Manchester City in the summer, but the deal did not take shape.
Kluivert and van de Beek have managed to establish themselves as first-team players at Ajax and have caught the eye of the Spurs hierarchy.
Everton were believed to be interested in signing Dost when Ronald Koeman was in charge at Goodison Park.
Arsenal shareholders will have the chance to question the club's hierarchy at their annual general meeting on 26 October.
Lindelof was at fault for Huddersfield's second goal in United's 2-1 defeat at the John Smith's Stadium.
Tottenham Hotspur take on West Ham in the Carabao Cup fourth round on Thursday with Juan Foyth in contention to start his second game for the club.