United's Europa League campaign comes to an end. Liverpool have produced a thoroughly professional performance away from home to take the tie 3-1 on aggregate, having killed the game off with an equaliser on the stroke of half time.

FULL TIME

Manchester 1-1 Liverpool

Liverpool win 3-1 on aggregate and progress to the quarter-finals of the Europa League

De Gea again denies Origi and Darmian manages to get to the loose ball just before Allen and clear.

Origi almost finishes United off after a driving run into the box but it is a relatively comfortable save for De Gea. United started very brightly in this game, but their second-half performance has been utterly toothless.

Ryan Giggs is patrolling the touchline, screaming instructions to his players.

The resulting corner pinballs around the United box with a few rubbish efforts on goal blocked until Lingard takes responsibility, lashing a powerful effort just wide of the post.

The Stretford End screams for a handball as Valencia's cross hits Milner's arms but the appeals are turned down.

Schweinsteiger lifts it in but it is cleared by the first man. Blind picks up the pieces and tires an ambitious effort of his own, but it's sent well wide. 85 minutes of this match remaining, United don't look like scoring in the next five hours, let alone the next five minutes.

Jesse Lingard embarks on a hopeful drive forward on his own and gets into the final third before Firmino hauls him down and the Brazilian is booked.

Coutinho takes it, but lifts it well over the bar.

Schweinsteiger is now booked for a dreadful challenge on Lallana right on the edge of the box.

Firmino pulls another fine save out of De Gea but the Brazilian was offside as he lashed his effort on goal.

And Coutinho almost did there, getting the ball on the edge of the box and lashing a vicious effort on goal, but De Gea again is equal to it.

United are done here, no fight, no drive, nothing. It's a matter of time before Liverpool finish them off.

Liverpool almost finish United off. Can bursts down the inside left and knocks it back through Darmian's legs with a deft back heel, straight into Coutinho's path. He takes a touch before shooting, but it is straight at De Gea.

Rashford does brilliantly, exchanging one-twos with Valencia down the right before cutting a fine ball back for Fellaini. All he has to do is keep his composure, but he sends his effort well over the bar. Dismal effort.

Last roll of the dice for van Gaal, a half-fit Bastian Schweinsteiger is coming on for Carrick. Divock Origi meanwhile is on for Sturridge.

Utterly bizarre from United and Fellaini. The Belgian gets the ball on the edge of the box and has the time and space to turn. Instead, he turns again and passes behind him.

United aren't quite pedestrian in possession at the minute, but with 25 minutes to go they need to speed it up. Carrick is robbed of the ball by Can on the edge of his own box but luckily for him, Blind is on hand to clean up.

Neat interplay involving Valencia, Martial and Lingard sees United create another half chance, with the latter backheeling a lovely ball into the Frenchman's path, but he smashes it clean over the bar.

Coutinho dances past three meek challenges from United players with an eye for goal, but instead slots it to Sturridge who fires a wild one into the crowd. Sublime stuff from the Brazilian.

United are having their share of half-chances, but they haven't forced Mignolet into a good save since Lingard's header in the first half. Liverpool are lying wait on the break.

Another big chance passes United by. Carrick swings in a beauty of a cross from deep that is telegraphed for Fellaini 's head, but his header is a tame one straight at Mignolet.

Another change for United, Matteo Darmain is coming on for Rojo. Both full-backs changed with United pursuing three goals.

United venture forward down the right through Valencia who slides it into Mata. He looks inside too, scooping it into Rashford but the young striker chests it and lashes a miss hit shot wide all in one not-so-fluid motion. United desperately need to improve in the final third.

United defenders turn to statues as Smalling allows the ball to bounce and is then brushed off it by Sturridge. He only had Blind to beat but the Dutchman makes an important interception to save his defensive partner.

Martial again is United's bright spark, jinking into the box before sliding it through to Mata, but the Spaniard is easily dispossessed by Can, who is having a very good game.

Clyne is now booked for a silly challenge on Rashford and United have a free kick out on the left. Milner does his job at the near post however and forces it out.

Fellaini tussles with Lovren to reach another high ball and is shown a yellow card after his elbow catches the defender right in the ear.

Rashford lays one of for Rojo who swings another decent ball in from the left. Fellaini rises and doesn't look to get much on it, but replays show it came off his marker and United get the corner. Pity they waste it completely.

Valencia's contribution is a driven through ball down the inside right for Rashford but it comfortable enough for Mignolet to claim.

And we are back underway, United need to score three more and keep Liverpool at bay if they wish to progress.

A change for United ahead of the second half, Guillermo Varela is paying for letting Coutinho slip by him so easily, Antonio Valencia comes onto replace him.

Half-time: Manchester United 1-1 Liverpool

Liverpool find an equaliser on the stroke of half time! It's too easy for Coutinho as he dances in from the left, easily selling Varela a step-over, taking him out of the game before dinking a cheeky effort over de Gea. Huge goal.

Goal! Manchester United 1-1 Liverpool (Philippe Coutinho, 44)

What a chance for Rojo! Fellaini sprints to get onto the end of a long, searching ball, just about keeping it in play and cutting it back to the Argentine at the near post, but under heavy pressure from Sakho, fires wide.

Mata curls a low one into the near post but Milner easily hooks clear.

Lingard is freed down the right but Coutinho is all over him from the start having been caught wrong side of him. Yellow card for the Brazilian.

What a chance for Henderson! He starts a fine move from the middle, threading through for Coutinho who has moved into space. Henderson continues his run into the box and gets the ball back, but he lashes his first-time effort well over the bar.

Can easily fools Rojo down the left before floating a cross into the six yard box but Carrick reads it well and nuts clear.

Rashford is now freed down the inside right, picked out wonderfully by Carrick, and passes back across goal but his ball evades all of his teammates inside the box and Liverpool clear.

Mata opts to lift an outswinging cross in but it is nutted away by Can.

Now United have a free kick in the exact same position from where Sturridge just took his.

Sturridge denied by the bar! From a extremely tight angle, the striker lashes the free-kick over the wall and over De Gea, but the woodwork keeps it out. Wonderful effort.

Liverpool attack immediately and Sturridge is tripped on the edge of the box.

Martial dusts himself off and drills it past Mignolet. Game on!

Goal! Manchester United 1-0 Liverpool (Anthony Martial, 31)

Martial takes on Clyne again and wins again, tripping over the full-back's leg inside the box. The ref points to the spot!

PENALTY - Manchester United

Firmino controls a fizzing pass from Lallana, takes it forward a couple of yards and lashes one on goal from 25 yards out. It's moving in the air and bounces off the turf on its way, but De Gea follows it all the way and saves again.

De Gea saves again! Firmino flicks it into Coutinho's path on the edge of the box and Blind takes an age to get across. Coutinho fires low and hard but the United goalkeeper gets down swiftly to palm it away.

Just over 15 minutes remain of this very open first half.

Off that, Liverpool counter quickly and the ball is pulled back invitingly for Coutinho on the edge of the box. Luckily for United, his first touch is horrid and Carrick can step in to clean up.

Martial again drives down the left, beating Clyne and drawing Lovren across before sliding a pass into the six yard area. Rashford is there but is well marshalled by Sakho and the ball is cleared.

Rashford gives Can the slip easily and shifts the ball out to Martial, who veers inside to take on Clyne. He clips the ball over him beautifully and win Lallana advancing, lashes one on goal from a tight angle, but can't find the target.

Can, for the second or third time, easily shifts Varela off the ball to win it back.

Liverpool fail to clear the resulting corner and the ball falls to Mata who clips a half volley across goal, looking for the far post, but it veers just wide.

Mignolet denies Lingard! Marial cuts a pass back to Rojo who digs out a decent cross out from the left. Lingard watches it fall out of the sky and gets his head on it, but there isn't enough direction on it to beat the Liverpool goalkeeper.

Fellaini shows neat footwork (!!!) down the left to slip between two challenges before forcing the ball onto Martial, who is faced by Sturridge in a defensive position. The Liverpool striker does well, however, reading his run inside and intercepting.

Mata almost clips one through for Mata after a really poor pass across goal from Lovren but the centre-half manages to get across and force out for a corner. The set piece goes back to Rojo who swings a cross into the box, but it is an easy catch for Mignolet.

No chances of note yet, Rashford tries to force one with a surging run down the right but again Sakho marshalls him well. The youngster had no real support there, either.

Milner whips a decent ball into the box that Rojo clears and United try to break, sending a searching ball down the left for Martial, but Clyne gets across to cut it out.

There's a decent tempo to this game in the opening 10 minutes, fairly balanced so far.

Mata sweeps an ambitious ball out to his left but he overhits it and there is nothing Martial can do to keep that in.

Lallana picks up a loose ball on the edge of the box and dances past a few challenges as he cuts across, looking for the opening. It doesn't come, and pass goes backwards, eventually all the way to Mignolet.

Mata misplaces a pass but Smalling pushes up and wins it straight back. Positive start from United, full of energy.

Mata forces the issue early, hooking a ball over for Rashford who almost gets the better of Sakho, but the Frenchman recovers well and wins a goal kick for his side.

And Liverpool get us underway. Here we go.

Coutinho looks like he will start wider than he usually does this evening, Klopp looks to have selected a 4-4-1-1 with Firmino in behind Sturridge.

Jesse Lingard at 23 is the grand old man of United's attack alongside Anthony Martial and Marcus Rashford.

United must start quickly here, they didn't for one minute match Liverpool's intensity last week, that cannot be the case tonight.

Both teams are in the tunnel, about to make their way out onto the pitch. Almost time...

Just over 10 minutes until kick off at Old Trafford. Here's another look at those teams.

Manchester United team to face Liverpool: De Gea, Varela, Smalling, Blind, Rojo, Carrick, Fellaini, Lingard, Mata, Martial, Rashford

Subs: Darmian, Valencia, Williams, Schneiderlin, Schweinsteiger, Memphis

Liverpool team to face Manchester United: Mignolet, Clyne, Lovren, Sakho, Milner, Can, Henderson, Lallana, Coutinho, Firmino, Sturridge

Subs: Ward, Toure, Smith, Allen, Ibe, Origi, Benteke

If you fancy following Tottenham Hotspur's attempts to claw their way back from 3-0 down against Borussia Dortmund this evening, you can keep up with our live coverage here.

Gay Neville has been sent to the stands at the Mestalla; he is fuming with the decision not to give his side a free-kick for a handball in the build up to Athletic's goal.

Elsewhere tonight, Sparta Prague are hammering Lazio in Rome and are on their way to securing a place in the quarter-finals with a 4-1 aggregate lead. It's still goalless between Bayer Leverkusen and Villarreal with the Spaniards leading on aggregate, while Athletic Bilbao have just scored at Valencia, drawing the tie at 2-2 but giving them a pivotal away goal.

Liverpool's only regrets meanwhile from that first leg is that they were unable to punish United further, with David de Gea denying them more. Jurgen Klopp insists his side will not go out there just to defend what they have got, however.

We know about the job we have to do," said the German. "We will try to play similar or more intensive.

"I am absolutely optimistic [that my team will put in a good performance]. We know that we know how to play them. It was a good night for us last week. But at the same time it's only halfway. We'll go into the game confident we can finish the job.

United were thoroughly miserable in their performance at Anfield a week ago and Louis van Gaal knows his side having some making up to do.

We have to believe in it. I have spoken only with the players about the victory.

"We always owe to the fans a big result because the fans are paying to see that. We have to deliver.

17-year-old RoShaun Williams is on the bench once again for United this evening,

Louis van Gaal has selected the ever-popular Fellaini in midfield with Bastian Schweinsteiger on the bench. The German was instrumental in helping United rescue a replay with West Ham in the FA Cup on Sunday. Daley Blind starts despite claims earlier today he was out of the squad. Anders Herrera is out of the 18, however.

Just the one change made by Jurgen Klopp this evening, then, an enforced one. Skipper James Milner comes in at left-back in the place of the injured Alberto Moreno. The trio of Adam Lallana, Roberto Firmino and Philippe Coutinho all start behind Daniel Sturridge.

BREAKING: Fellaini starts in midfield alongside Michael Carrick, Marcus Rashford continues up front. Bastian Schweinsteiger makes the bench.

Manchester United team to face Liverpool: De Gea, Varela, Smalling, Blind, Rojo, Carrick, Fellaini, Lingard, Mata, Martial, Rashford

Subs: Darmian, Valencia, Williams, Schneiderlin, Schweinsteiger, Memphis

BREAKING: Alberto Moreno misses out with that hamstring injury, James Milner slots in at left back.

Liverpool team to face Manchester United: Mignolet, Clyne, Lovren, Sakho, Milner, Can, Henderson, Lallana, Coutinho, Firmino, Sturridge

Subs: Ward, Toure, Smith, Allen, Ibe, Origi, Benteke

Marouane Fellaini could have been suspended for tonight but escaped punishment for that elbow on Emre Can in the dying stages of last week's match. With Schweinsteiger and Ander Herrera unavailable, the Belgian could feature.

I cannot say if he plays tomorrow because then I give away a part of my line-up and I don't want to do that," the boss said. "But Fellaini has his way of playing and he can give us a lot of qualities. He has contributed to a lot of games in a very good way and for me it's very important, if he can contribute in the game plan that we have created with each other.

Ashley Young and Cameron Borthwick-Jackson have returned to training but are unlikely to be risked tonight. Bastian Schweinsteiger is also is not ready, according to Louis van Gaal, despite his positive impact off the bench against West Ham United on Sunday. Van Gaal said of the German:

[Schweinsteiger] has played two times 10 or 15 minutes, maybe he can play 45 minutes or 30 minutes depending on the situation on the pitch," the boss said. "I cannot say in advance but I try to do that.

"His impact was very big in the game versus West Ham United and he was involved in the goal. But I have to cope with the fact when they're injured, you're not back at the moment they train one training session with you.

United have had some desperately poor nights in Europe over the last 10 years. Lille 2005. Basel 2011. Olympiakos 2014. The first leg against Midtjylland just last month. Last week's performance against Liverpool was right up there and perhaps, the hardest to swallow. United were vile at Anfield and would have been humiliated by their arch-rivals, had it not been for the heroics of David de Gea. His saves ensure United are still in the contest ahead of the second leg this evening.

Anything that even slightly resembles that wretched performance at Anfield will see United eliminated from the Europa League and surely push Louis van Gaal closer to the Old Trafford exit.

We saw both sides of United in the last 32 ties against Midtjylland – the dismal, spineless one that gave up so easily and Denmark and the vibrant, reinvigorated bunch that lit up Old Trafford a week later. They will have to do that again tonight. Anything else against their oldest rivals, on this stage, will be unacceptable.