Wilshere has played regularly since he joined the Cherries.
Ozil already has seven goals so far this season, as well as three assists.
Alexis Sanchez suffered a muscular injury while training with Chile.
Ozil has scored seven goals in his last 14 appearances for the Gunners.
Wilshere is on a season-long loan to Bournemouth.
Alexis has been ruled out for the Chile trip to Colombia due to a muscle injury.
Striker was disappointed not to start in the north London derby after goals against Sunderland and Ludogorets.
Mesut Ozil joined Arsenal from Real Madrid in 2013.
The Gunners squandered the chance to move to the top of the Premier League table.
Arsenal and Tottenham played out a draw for the 24th time in north London derby history.
Gunners missed out on the chance to go top of the Premier League.
Campbell says Arsenal and Tottenham had a chance to win the title last season.
Shkodran Mustafi joined Arsenal from Valencia in August.
Spanish defender appeared to come through training session after muscle injury.
Xhaka, 24, has been sent off twice from club and country this season.
Hector Bellerin missed the clash against Ludogorets after a minor incident in training.
Granit Xhaka, Olivier Giroud and Mesut Ozil as north Londoners book place in the last 16.
Giroud scored with his first two touches against Sunderland.
Giroud scored two goals with his first two touches against Sunderland on 29 October.
Arsene Wenger has decided to rest Theo Walcott and Hector Bellerin for the game in Bulgaria.
Arsenal will have one eye on the north London derby when they travel to Bulgaria to take on Ludogorets in the Champions League.
Ramsey returned to the first-team after over two months during Arsenal's win over Sunderland.