Brand now in a happy relationship with Laura Gallacher, with whom he shares daughter Mabel.
Radiohead, Ed Sheeran and Foo Fighters previously confirmed to headline in June.
Mayer and Perry dated on and off between 2012 and 2015 and collaborated on Who You Love in 2013.
Bloom and Perry announced they were parting ways in early March.
Radio station's annual music event taking place in Hull on 27 and 28 May.
Bloom and Perry announced their split on 1 March.
Justin Timberlake, Bruno Mars and Ed Sheeran performed at the California awards show on 5 March.
Bloom isn't 'ready to be tied down' and didn't want things to get more serious with Perry, claims a report.
Guns N' Roses, Ed Sheeran and Katy Perry also big contenders to front Pyramid Stage this summer.
Former couple released joint statement stating they were "taking respectful, loving space".
Formation singer, who is pregnant with twins, was forced to pull out of performance on doctor's orders.
A giant skeletal Donald Trump and Theresa May joined Perry on stage at the Brit Awards 2017.
Bowie was posthumously awarded Best Album for Blackstar and also named Best British Male.
Other big winners of the night included Little Mix taking British single and Emeli Sande winning British female.
Ellie Goulding, Little Mix and Mollie King brought rock star glamour to the Brits but so many stars got it so wrong.
Song serves as the lead single for Perry's upcoming fourth studio album.
Perry joins Ed Sheeran, The 1975, Bruno Mars and Skepta on the star-studded line-up.
The best dressed celebrities at this year's music awards ceremony.
The event was hosted by James Corden and saw performances from Adele, Beyonce, Lady Gaga and Metallica.
Perry, 32, performed her new single Chained To The Rhythm at the music awards ceremony.
Perry will perform the song live for the first time at the Grammys 2017 on Sunday 12 February.
Perry is expected to debut her new single at the Los Angeles awards ceremony on 12 February.