Aaron Cresswell received his first-ever call-up to the senior England squad.
Walker was taken off with 10 minutes remaining against Arsenal on Sunday.
Arsenal and Tottenham played out a draw for the 24th time in north London derby history.
Harry Kane has missed Tottenham's last 10 games with an ankle injury.
Spanish defender appeared to come through training session after muscle injury.
Hector Bellerin missed the clash against Ludogorets after a minor incident in training.
Kane damaged ankle ligaments during Tottenham's win over Sunderland on 18 September.
Naby Keita joined RB Leipzig from Red Bull Salzburg in Austria.
Origi was forced off in the second-half of Liverpool's win over Tottenham with a cramp.
The last three games between Liverpool and Tottenham have ended in draws.
Jack Wilshere is on a season-long loan at Bournemouth with fitness being the main objective.
Sissoko elbowed Harry Arter in the final stages of Tottenham's draw against Bournemouth.
Wilshere last played the full 90 minutes against Manchester City in September 2014.
Three people were trapped on the top deck of the bus and were rescued by firefighters.
Tottenham remain the only unbeaten side in the Premier League thus far.
Alderweireld suffered a knee injury against West Bromwich Albion.
Toby Alderweireld was stretchered off 15 minutes into the second-half.
Danny Rose would welcome the French coach as the replacement for Sam Allardyce.
Harry Kane has missed the last four games with ankle ligament injury.
Burke joined RB Leipzig from Nottingham Forest this summer.
Georges-Kevin N'koudou has played just one minute of Premier League football this season.
Eric Dier and Danny Rose missed Tottenham's last three and six games respectively.