Tony Pulis plans to assess a number of potential injury victims during a final training session on Friday.
Eric Bailly, Luke Shaw and Henrikh Mkhitaryan will all miss the Saturday teatime kick-off.
Blues have being charged over player behaviour five times in the last 19 months.
Antonio Conte's side go back to the top of the Premier League.
Tony Pulis is unbeaten in his last four games against Chelsea.
Manchester City are winless in their last six games in all competitions.
Reds have only kept one clean sheet in their nine league games this season.
Philippe Coutinho and Sadio Mane on target as Jurgen Klopp's side extend their unbeaten home run to 17 games.
Liverpool and West Bromwich Albion face each other in the Premier League tie on 22 October.
Tony Pulis claims he is not disappointed with striker, despite reports that he is eight pounds overweight.
Spurs maintain their unbeaten record but fail to win at The Hawthorns.
The Venezuelan travelled to both Montevideo and Merida during a busy international break.
Tottenham face West Brom after defeating Manchester City in the last league fixture.
Spurs boss is hopeful that Harry Kane could start training outside next week after an ankle problem.
Arsenal and Leicester also ease to victory on a goal-laden Saturday of Premier League football.
New owner Guochuan Lai 'delighted' to complete purchase of The Hawthorns club as Jeremy Peace leaves.
Striker's former bosses tell IBTimes UK what we can expect from Spaniard at the Emirates.
Baggies star Saido Berahino's emergence is credited to Steve Hopcroft.
Belgium international thrilled to be Baggies' record signing.
Sakho, 26, is reported to have turned down moves to West Brom, Stoke and Besiktas during the transfer window.
Manchester City striker Sergio Aguero could be in hot water after appearing to elbow Winston Reid.
Nottingham Forest winger Oliver Burke, 19, is also attracting interest from Bayern Munich.