Israel bombarded Gaza with artillery and air strikes on Friday in response to a new barrage of rocket fire from the Hamas-run enclave, in an intensification of a conflict that has now claimed more than 100 Palestinian lives.

Days of deadly violence have seen Israeli soldiers massing on the edge of the territory, although the army stressed there had been no ground incursion despite an earlier statement that troops were carrying out an attack "in the Gaza Strip".

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Israeli seurity forces advance amid clashes with Palestinian protesters at the al-Aqsa mosque compound in Jerusalem Photo: AFP / Ahmad GHARABLI

Israeli security forces have also been scrambled to contain deadly riots between Jews and Arabs, and projectiles have been fired from Lebanon.

Images early Friday showed large balls of flame turning the night sky orange in densely packed Gaza, while rockets were seen tracing through the air towards Israel.

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Map of Jerusalem's Old City Photo: AFP / AFP

The United Nations said the Security Council would meet on Sunday to address the conflict as the world body's Secretary General called for "an immediate de-escalation and cessation of hostilities".

"Too many innocent civilians have already died," Antonio Guterres tweeted. "This conflict can only increase radicalization and extremism in the whole region."

US Secretary of State Antony Blinken said Washington was "deeply concerned about the violence in the streets of Israel", and the State Department urged citizens to "reconsider travel to Israel".

Several international airlines -- including KLM, British Airways, Virgin, Lufthansa and Iberia -- cancelled flights amid the aerial onslaught.

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An injured Palestinian protestor is helped during clashes with Israeli police in Sheikh Jarrah in east Jerusalem Photo: AFP / EMMANUEL DUNAND

Dozens of rockets were fired from Gaza towards the southern Israeli coastal cities of Ashdod and Ashkelon, and in the vicinity of Tel Aviv's Ben Gurion airport.

Israeli army spokesman John Conricus said the country was "prepared...for various scenarios", describing a ground offensive as "one scenario".

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An Israeli sapper checks a damaged apartment in the southern Israeli city of Ashkelon after rockets were fired by the Hamas movement from the Gaza Strip towards Israel overnight Photo: AFP / JACK GUEZ

In Gaza, AFP photographers said people were evacuating their homes in the northeastern part of the enclave ahead of possible Israeli attacks, with Hamas, the Islamist group that controls Gaza, warning of a "heavy response" to any ground incursion.

The Israeli army clarified early Friday that its troops had not entered the Gaza Strip as it had earlier indicated, blaming an "internal communication" problem for the confusion.

With the conflict showing no signs of easing, Israel has been rocked by an unprecedented wave of mob violence, in which both Arabs and Jews have been savagely beaten and police stations attacked.

Defence Minister Benny Gantz ordered a "massive reinforcement" to suppress the internal unrest.

The heavy bombardments coincided with the start of Eid al-Fitr, which marks the end of the Muslim holy fasting month of Ramadan, and saw the faithful pray at mosques and amid the rubble of Gaza's collapsed buildings.

Israel's air force launched multiple air strikes, targeting locations linked to Hamas, with the air force saying jets had struck a "military compound" of the group's "intelligence headquarters".

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Palestinian faithful hold night-time prayers in front of the Dome of the Rock in the Old City of Israeli-annexed east Jerusalem Photo: AFP / Ahmad GHARABLI

At least 103 people have been killed since Monday, including 27 children, and more than 580 wounded, the health ministry in Gaza said.

Heavy bombardments have brought down entire tower blocks.

Inside Israel, seven people have been killed since Monday, including one six-year-old, after a rocket struck a family home.

The Israeli military said it had hit targets in Gaza more than 600 times while 1,750 rockets were fired from the enclave.

Hundreds of rockets were intercepted by the Iron Dome air defence system.

Three rockets were also fired from southern Lebanon towards Israel, landing in the Mediterranean Sea, Israel's army said.

A source close to Israel's arch-enemy Hezbollah said the Lebanese Shiite group had no link to the incident.

The military escalation was triggered by weekend unrest at Jerusalem's Al-Aqsa mosque compound, which is sacred to both Muslims and Jews.

The disturbances, in which riot police had repeatedly clashed with Palestinians, has been driven by anger over the looming evictions of Palestinian families from the Sheikh Jarrah neighbourhood of east Jerusalem.

The surging tensions sparked clashes in many of Israel's mixed towns where Jews live alongside Arabs, who make up about 20 percent of the country's population.

Nearly 1,000 border police were called in to quell the violence, and more than 400 people were arrested.

Police spokesman Micky Rosenfeld said inter-communal violence in multiple towns was at a level not seen for decades, and that police were "literally preventing pogroms".

Prime Minister Benjamin Netanyahu said police were increasing their use of force, warning of the "option" of deploying soldiers in towns.

Israeli far-right groups have clashed with security forces and Arab Israelis, with television footage Wednesday showing a far-right mob beating a man they considered an Arab in Bat Yam, near Tel Aviv, leaving him with serious injuries.

In Lod, which has become a flashpoint of Arab-Jewish clashes this week with an Arab resident shot dead and a synagogue torched, a gunman opened fire Thursday at a group of Jews, wounding one.

Netanyahu said the violence was "unacceptable".

"Nothing justifies the lynching of Arabs by Jews, and nothing justifies the lynching of Jews by Arabs," he said, adding Israel was fighting a battle "on two fronts".

Hamas announced it had also fired a rocket at Ramon in a bid to stop air traffic to Israel.

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