La Liga leaders host Malaga following two consecutive defeats to Sevilla and Celta Vigo.
Argentina international yet to sign a new deal amid Manchester City transfer links.
Ballon d'Or was rested in previous two rounds against Cultural Leonesa and Sevilla.
The Manchester United star hails Barcelona ace as "the future and the present" of football.
Champions League winners beat Jorge Sampaoli's side 3-0 in the first leg.
La Liga superstars continue to dominate football's individual accolades.
Cristiano Ronaldo and Lionel Messi once again refused to vote for each other.
Ronaldo won the Champions League with Real Madrid and Euro 2016 with Portugal last year.
Cristiano Ronaldo defeats arch-rival Lionel Messi to scoop the Best Fifa Men's Player Award in Zurich.
Ronaldo, Messi and Griezmann will compete for the Best Fifa Men's Player Award 2016.
Portugal international is back in Zidane's 19-man squad after being rested against Sevilla.
Los Blancos took a huge step towards the last eight of the Copa del Rey with a 3-0 victory.
Los Blancos host the Europa League winners on Wednesday before a La Liga clash with Granada.
Real are chasing records, while the Catalans have some catching up to do.
Recent reports claim that Jose Mourinho is likely to meet his £84.6m release clause in the summer.
Ronaldo has scored 22 goals for club and country this season.
The Real Madrid football star sent a message to children in war-torn Syria calling them heroes.
Former Olympic champion insists he will not achieve legendary status even if he beats Klitschko.
Leicester City winger Riyad Mahrez has also been included by Uefa.com in their fantasy team.
Zinedine Zidane doesn't know whether the captain will be ready for Sunday's final.
Prolific Bayern Munich striker scored 42 goals for the reigning Bundesliga champions last season.
Ronaldo won the Champions League with Real and the Euro 2016 with Portugal.