Liverpool have never lost to a side from England's fourth-tier in the FA Cup.
Kurt Zouma and Michy Batshuayi will start for Chelsea.
Ake has spent the first-half of the season on loan at Bournemouth.
Mertesacker is yet to play this season after suffering a knee injury during pre-season.
The last meeting between the two sides in the FA Cup was in 1999 when Arsenal won 4-2.
Manchester United are the holders of the FA Cup and will start their defence against Reading.
Michy Batshuayi expected to come in for Diego Costa.
The 23-year-old arrived on loan from Manchester United on Thursday.
Treble-winning defender heads back to Old Trafford in the third round of the FA Cup.
West Ham lost the league fixture against Manchester City 3-1.
Daniel Sturridge doubtful after suffering an injury against Sunderland.
Gunners boss reveals latest on Lucas Perez, Mesut Ozil, Francis Coquelin, Danny Welbeck and Theo Walcott.
Gunners boss confirms Mesut Ozil will miss third game in a row at Preston North End in the FA Cup.
32 third round ties will be played across the 7, 8 and 9 of January 2017.
Premier League and Championship clubs enter the fray as minnows eye further upsets.
Ramsey has recalled the circumstances surrounding his transfer to Arsenal.
IBTimes UK provides key information ahead of the draw, including dates and those all-important ball numbers.
Wenger was introduced as the Arsenal manager in September 1996.
The 34-year-old joined the Gunners on loan in 2014.
This follows May's confirmation that last-eight replays in the competition will be scrapped this season.
Ex-Gunners captain could soon join the club's coaching staff.
The Met Police has launched an appeal after a man and woman were targeted at north London train station.