Reports claim Jose Mourinho wants him at Old Trafford next season.
Former Manchester United star left pitch furious with Zinedine Zidane's decision.
Athletic Club are 5th in La Liga after not signing a single player last summer.
Real Madrid visit the Signal Iduna Park following draw with Las Palmas.
Ronaldo appeared unhappy after he was taken off in Real's 2-2 draw with Las Palmas.
Real Madrid looking to return to winning ways at Estadio Gran Canaria.
Barcelona can go top of the La Liga table by winning at El Molinon.
Brazilian is currently on loan at Sporting Gijon.
Spaniard has been left out of the Catalans' squad for the last three games.
Spaniard would snub Manchester City as he wants to renew his current deal which is set to expire in 2018.
Messi, 29, will miss two La Liga matches and Champions League meeting with Borussia Monchengladbach.
Catalans announced agreement with the Spain international in May.
Barcelona face a stern test of their mettle against Diego Simeone's side at Camp Nou.
Real Madrid out to break all-time La Liga record for consecutive wins.
Belgian keeper compared current United boss to former manager Diego Simeone.
Isco is out of favour in Madrid and could be attainable for a fee of around £25m.
Sight of the two stars coming off was seen as a big deal until last season.
Duo missed the 2-0 victory over Espanyol due to illness and injury respectively.
Valencia full-back Joao Cancelo and Shakhtar Donetsk star Darijo Srna are the other candidates.
Real Madrid looking to continue perfect start to season at Cornella-El Prat.
Manager Zinedine Zidane is unwilling to take a risk on either player amid throat and hip problems.
Catalans travel to Leganes only four days before a home game with Atletico Madrid.