Barcelona's attacking trio of Neymar, Luis Suarez and Lionel Messi proved too strong.
The Gunners boss believes his side could have created a "sensation" had they taken a 2-1 lead at the Nou Camp.
Barcelona will be without the suspended Pique, as well as the injured Rafinha and Sandro
Arsenal have never managed to progress into the next round at the expense of Barcelona.
Argentine has room for improvement however after missing eighth penalty for the Catalans.
Barcelona technical director Robert Fernandez discusses the club summer transfer plans.
The 27-year-old Argentine has revealed he hopes to return to his homeland after the next World Cup.
Spaniard also backed Mikel Arteta to have a successful future as a manager.
Former Manchester United defender feels Gunners would be better served by concentrating on Premier League.
Two Nigerian men have a deadly row over who is the best footballer in the world in Mumbai suburb.
Barcelona centre-back also ruled out a return to Old Trafford as he is happy at the Nou Camp.
'Messi's biggest fan' receives signed Argentina shirt and football from the legend himself.
German defender deflects blame for loss which leaves Gunners' European ambitions hanging by a thread.
The retired defender admits the Gunners need to bridge a sizeable gap between themselves and Europe's elite.
Wenger was left particularly frustrated after his side allowed themselves to concede via a counter-attack.
Manchester United star previews the game between his compatriots and his Premier League rivals.
The 25-year-old defender will miss the much-anticipated tie with an injury.
The 55-year-old Spaniard has offered his thoughts on the much-anticipated Champions League clash.
Arsenal will aim to beat beat Barcelona to progress in the Champions League
The club's economic vice president is convinced that Neymar will renew his contract with Barcelona.
Arda Turan is the major absence for Barcelona as a result of a suspension.
The 24-year-old Brazilian has been in sensational form this season at the Nou Camp.