Cuoco plays Penny in the hit CBS sitcom The Big Bang Theory.
The cluster is the most distant ever to be detected and formed two-and-a-half billion years after the Big Bang.
Helberg will next be seen alongside Meryl Streep and Hugh Grant in the upcoming movie Florence Foster Jenkins.
A tabloid had claimed that the actress was igniting bad blood among the cast of the show.
The Big Bang Theory star apologised for posting a picture of her dogs posing on an American flag.
Fox dropped American Idol while CBS has no CSI series planned for the coming TV season.
The Big Bang Theory actor Simon Helberg also features as supporting character Cosmé McMoon.
The show airs every Thursday at 8pm ET/PT on CBS network.
The actor made his TV breakthrough with the leading role in the US sitcom.
Check out the complete list of winners in the TV, movie, music, book and game categories.
Kaley Cuoco and Jim Parsons say they're still keen to continue
Cast of hit shows, including The Big Bang Theory, Two and a Half Men, will also be present at the TV event.
Study found quark-gluon plasma behaved like a liquid and had an elliptical shape like a rugby ball.
A number of familiar guests will also be part of the milestone episode.
Study details how we can finally understand what caused the Big Bang Theory – rapid expansion, or contraction.
The James Burrows tribute special airs on NBC on 21 February.
Physicists propose new theory that says there were periods of inflation after the Big Bang.
Glee alumna Jane Lynch hosted the 42nd People's Choice Awards.
New Hampshire teacher Edith Newlin originally wrote a poem about a soft kitty in the 1930s.
The show's season 5 finale was downloaded illegally via BitTorrent 14.4 million times.
As Spider-Man's and the Hulk's creator Stan Lee turns 93 today, IBTimes looks at his rise to become one of the most recognisable faces in comic books.
Astronomers are probing back in time to look for the oldest stars, says expert on early universe.