Arsenal will have one eye on the north London derby when they travel to Bulgaria to take on Ludogorets in the Champions League.
Anfield outfit has not won the league title since 1990.
Antonio Valencia suffered the injury during United's win over City in the EFL Cup.
Messi is preparing to face Guardiola's Manchester City in the Champions League.
Premier League leaders out to avenge 4-0 defeat in the reverse fixture at Camp Nou.
Ramsey returned to the first-team after over two months during Arsenal's win over Sunderland.
Ibrahimovic, 35, has failed to score in his last six Premier League appearances.
Raiola helped to engineer Pogba's return to Old Trafford over the summer.
The Stamford Bridge club won thanks to Eden Hazard and their Spanish striker.
Bale, 27, has been a huge success since joining the Spanish club in 2013.
Italian manager expects Blues to be in the running for the league title this season.
Jose Mourinho is already facing a charge for his comments over referee Anthony Taylor.
Arsenal are unbeaten in nine games in the league.
Boss left frustrated with the 1-1 draw against Leicester City.
Southampton can move above Manchester United with a win over Chelsea.
Neville says United could have scored 'six, seven or eight' goals at Old Trafford.
Wilshere missed the entirety of last season with an injury.
Rooney started from the bench in Manchester United's 0-0 draw against Burnley.
Shmed Musa equalised after half-time as the Foxes claimed their first away point of the season.
The Reds win a thrilling game in south London.
Valencia has been a star player for Manchester United under Jose Mourinho.
United could not find a way past Tom Heaton.
Rooney, 31, joined United from the Toffees in 2004.
The Gunners top the table after their one-sided win.
Pogba, 23, joined United from Juventus during the summer transfer window.
Coutinho has scored five goals and provided three assists in 10 games in all competitions.
Rooney, 31, has been demoted to the bench at Old Trafford in recent weeks.
Benteke, 25, was sold by the Reds during the summer transfer window.
The Nigerian has become a key figure for the Gunners this season.
Christian Benteke will lead Palace against his former club Liverpool in the league fixture on Saturday.