Handler commented that celebrity divorce lawyer Laura Wasser was 'negotiating Brad Pitt's emancipation'.
Actor's friends – George Clooney and Julia Roberts – helped him get through the divorce drama, as per reports.
The French actress was linked to her Allied co-star soon after Jolie filed for divorce.
Pitt and Jolie filed for divorce in September, 2016.
Jolie filed for divorce from Pitt in September, 2016.
It was earlier reported that the pair's friendship had caused problems in Pitt's marriage with Jolie.
The French actress was initially blamed for the highly publicised separation of the former Hollywood couple.
The former couple share six children – Maddox 15, Pax, 12, Zahara, 11, Shiloh, 10, and twins Knox and Vivienne, 8.
The Original Sin actress filed for divorce from the Allied star on 19 September.
He said he appreciated everybody's concern and prayers for the separating couple.
The Allied actor was cleared of abuse allegations by the Los Angeles Department of Children and Family Services.
The pair married in 2000 after meeting each other in 1999.
Hollywood couple announced imminent divorce back in September.
Pitt was accompanied by friend Julia Roberts at the private screening of his film Moonlight in Los Angeles.
The Department of Child and Family Services has cleared Pitt of child abuse allegations.
Couple announced their split in September.
Jolie filed for divorce from Pitt on 19 September.
Jolie's representative has confirmed that Brangelina has reached another custody agreement.
Friends star says, 'All I know is that I feel completely seen, and adored, in no matter what state.'
The former couple has now decided that Jolie will continue to have sole custody, while Pitt gets 'therapeutic visits' of their children.
The actor has cancelled all interviews for the film due to the controversy surrounding his divorce.
The actor filed for divorce on citing irreconcilable differences.