In-form defender Kyle Bartley is relieved that Philippe Coutinho will also miss EFL Cup quarter-final tie.
Michael Carrick reportedly picked up an injury before West Ham United clash.
Michael Parker and Nicholas Greenway were both arrested at the game for their part in the disorder.
Antonio Valencia broke his arm during United's League Cup win over City on 27 October.
Reds are third in the table, despite playing a series of tough fixtures.
Milner, 30, missed Liverpool's EFL Cup win against Tottenham Hotspur due to illness.
Manchester United progressed to the quarter-finals of the EFL Cup with a win over City.
Mignolet has been replaced by Loris Karius in goal for the Reds.
Seven arrests were made in the aftermath of Wednesday night's violence.
More violence at Hammers' new stadium occurs during cup game with cross-city rivals
Cheikhou Kouyate and Edimilson Fernandes scored for West Ham United against Chelsea.
Cheikhou Kouyate and Edimilson Fernandes gave the Hammers the victory in the EFL Cup.
Juan Mata scored the only goal in Manchester United's win over Manchester City.
Chris Smalling has joined Eric Bailly on the injured list and is a doubt for Burnley clash.
Iwobi, 20, has quickly become an important figure for the North London club.
Trouble at the London Stadium marred an important victory for the Hammers at their new home in Stratford.
Liverpool also get home tie with Leeds United while Newcastle travel to Hull.
City failed to register a single shot on target during disappointing evening.
Cesar Azpilicueta, David Luiz and Gary Cahill comprised three-man defence in the win over Manchester United.
The out of favour England international scored two goals against Spurs at Anfield.
Jenkinson made his first Arsenal appearance in 898 days.
Eric Bailly ruled out with Marouane Fellaini a major injury doubt.